Pushing The Boundaries In Stroke Innovation
Novel device to minimise Ischemic reperfusion injury post thrombectomy.
Our Mission
Carefuse Medical is dedicated to creating innovative medical devices to minimize ischemic reperfusion injury post-thrombectomy. For inquiries or partnerships, please reach out to us. Your collaboration fuels our mission to improve patient outcomes.
WHAT IS REPERFUSION INJURY
Reperfusion Injury is characterized by an initial restriction of blood supply to the brain followed by the subsequent restoration/ re-introduction of oxygen and enriched blood into the brain tissues, which are starved of oxygen, such as is the case with ischemic stroke.
While existing therapies (i.e. Aspiration or Mechanical Thrombectomy) are very successful at clot removal they cannot treat Reperfusion Injury.
The removal of a clot is a key step in achieving positive patient outcomes. However, restoring blood flow without addressing reperfusion injury will never lead to 100% success. The divergence between clot removal rates and positive outcomes is evidence of this.
UNMET CLINICAL NEED
Of those patients who undergo “successful” thrombectomy (76,000 Cases alone in the USA by 2028), unfortunately only approximately 46% achieve a positive outcome.
The remaining 54% do not attain good outcomes despite timely and complete recanalization. This poor outcome is linked to reperfusion injury. (Ref: DOI: 10.1161/Stroke AHA.)
The cost of patient care for those with poor outcomes forms most of the cost of stroke care due to the long-term disability and presents a significant market opportunity of > $20bn in the USA alone.